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ISOSORBIDE DINITRATE
SynDRA canonical compound SYN0000038 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GUCY1B1 |
|---|
| Mechanism of action | Guanylate cyclase stimulant |
|---|
| Indication | angina pectoris | coronary artery disease (CAD) |
|---|
| Disease area | cardiology |
|---|
All known targets
- GUCY1A2
- GUCY1A3
- GUCY1B2
- GUCY1B3
- NPR1
- GUCY1A1
- GUCY1B1
Mechanisms of action (all sources)
- Nitric oxide stimulant
- Guanylate cyclase stimulant
- GUCY1B2 ACTIVATOR
- GUCY1A2 ACTIVATOR
- GUCY1A3 ACTIVATOR
- GUCY1B3 ACTIVATOR
Drug classes
- Nitrate Vasodilator
- Cardiovascular Agents
- Nitric Oxide Donors
- Vasodilator Agents
ATC classes
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- C01D · VASODILATORS USED IN CARDIAC DISEASES
Cross-references
Synonyms
- r-isosorbide dinitrate
- vascardin
- astridine
- Dinitrate d'isosorbide
- Dinitrato de isosorbida
- Diluted isosorbide dinitrate
- Isomannide-dinitrate
- Isosorbide dinitrate, diluted-
- Isosorbidi dinitras dilutes
- Isosorbidi dinitras dilutus
- Sorbide nitrate
- C01DA08
- NSC-80038
- Angitak
- Carvasin
- Cedocard
- Cedocard ret
- Cedocard-10
- Cedocard-20
- Cedocard-40
- Cedocard-5
- Dilatrate
- Dilatrate-sr
- Imtack
- Iso mack
- Isocard
- Isoket 10
- Isoket 20
- Isoket 5
- Isoket ret 20
- Isoket ret 40
- Isordil
- Isordil tembids
- Isosorbide dinitrate component of bidil
- Jeridin
- Soni-slo
- Sorbichew
- Sorbid sa
Reported adverse events
- Headache
- Hypotension
- Syncope
- Palpitations
- Vomiting
- Nausea
- Tinnitus
- Abdominal discomfort
- Amblyopia
- Asthenia
- Chromaturia
- Dizziness
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