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PHENYTOIN
SynDRA canonical compound SYN0000067 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN5A |
|---|
| Mechanism of action | Hydantoin antiepileptic |
|---|
| Indication | seizures |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN2A
- SCN1A
- SCN5A
- SCN3A
- SCN9A
- SCN8A
- SCN4A
- SCN7A
- SCN10A
- SCN11A
- Scn2a
- Scn1a
Mechanisms of action (all sources)
- Hydantoin antiepileptic
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Drug classes
- Anticonvulsants
- Cardiovascular Agents
- Central Nervous System Agents
- Cytochrome P-450 CYP1A2 Inducers
- Membrane Transport Modulators
- Metabolic Side Effects of Drugs and Substances
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
- Anti-epileptic Agent
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2C8 Inducers
ATC classes
Cross-references
Synonyms
- fenitoin
- sodium diphenylhydantoinate
- diphantoin
- diphenylan
- diphenylhydantoin
- phenytoine
- phenytoinum
- phenytoin sodium
- Phenytoine
- Fenitoina
- Diphenylhydantoin
- Epamin
- Lepitoin
- Phenytoinum
- Zentropil
- NSC-8722
- PHENYTOIN COMPONENT OF SM-88
- Dilabid
- Dilantin
- Dilantin-125
- Dilantin-30
- Hydantol
- Phentytoin
- Aleviatin
- Antisacer
- Auranile
- Causoin
- Citrullamon
- Citrulliamon
- Comital
- Comitoina
- Convul
- Danten
- Dantinal
- Dantoinal
- Dantoine
- Denyl
- Difenilhidantoina
Reported adverse events
- Dizziness
- Lymphadenopathy
- Stevens-Johnson syndrome
- Hypersensitivity
- Acute hepatic failure
- Hodgkin's disease
- Cerebellar atrophy
- Eosinophilia
- Angioedema
- Teratogenicity
- Porphyria
- Vitamin D
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