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CLOMIPRAMINE
SynDRA canonical compound SYN0000074 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | SERT inhibitor |
|---|
| Indication | obsessive compulsive disorder (OCD) |
|---|
| Disease area | neurology/psychiatry |
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All known targets
- SLC6A4
- SLC6A2
- SLC6A3
- ADRA1A
- GSTP1
- HTR2C
- HTR2A
- HTR2B
- Adra2a
- Htr6
- Htr1f
- Htr2a
Mechanisms of action (all sources)
- SERT inhibitor
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- ADRA1A ANTAGONIST
- SLC6A3 INHIBITOR
- SLC6A2 INHIBITOR
- serotonin transporter (SERT) inhibitor
Drug classes
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Selective Serotonin Reuptake Inhibitors
- Serotonin Agents
- Tricyclic Antidepressant
ATC classes
Cross-references
Synonyms
- chlorimipramine
- clomipramine hydrochloride
- clomipramine HCl
- Clomipramina
- 3-chloro-iminodibenzyl
- Anapramine
- Chlorimipramine
- Clomicalm
- NSC-169865
- Chlomipramine
- Clomipraminum
- Hydiphen
- Monochlorimipramine
- Anafranil base
- G 34586
- Anafranil (TN)
- Anafranil (free base)
- Clomipramina [INN-Spanish]
- Clomipramine (INN)
- Clomipramine [INN:BAN]
- Clomipraminum [INN-Latin]
- 10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5H-dibenz(b,f)azepine
- 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
- 3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
- 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
- 3-Chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine
- 3-Chloroimipramine
- 3-chloro-10,11-dihydro-N,N-dimethyl-5H-Dibenz(b,f)azepine-5-propanamine
- 5H-Dibenz(b,f)azepine, 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-(8CI)
- 3-Chloro-Iminodibenzyl
- NUV44L116D
- NSC 169865
- clomipramine (ema epar veterinary)
- DTXCID602844
- CHEBI:47780
- RefChem:58431
- Monohydrochloride, Clomipramine
Reported adverse events
- Suicide
- Headache
- Nausea
- Rash
- Tachycardia
- Vomiting
- Agitation
- Anxiety
- Constipation
- Cough
- Dysuria
- Increased appetite
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