PROPRANOLOL

SynDRA canonical compound SYN0000106 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ADRB3
Mechanism of action	Adrenergic receptor antagonist
Indication	angina pectoris \| hypertension \| migraine headache
Disease area	cardiology \| neurology/psychiatry

All known targets

ADRB2
ADRB1
ADRB3
HTR1A
ABCB1
HTR2B
SLC22A1
SLC10A1
SIGMAR1
Pgrmc1
NR2E1
Htr1b

Mechanisms of action (all sources)

Adrenergic receptor antagonist
ADRB1 ANTAGONIST
Beta-1 adrenergic receptor antagonist
ADRB2 ANTAGONIST
Beta-2 adrenergic receptor antagonist
HTR1A ANTAGONIST
HTR5A ANTAGONIST
ADRB3 ANTAGONIST
SLC10A1 INHIBITOR

Drug classes

Adrenergic beta-Antagonists
beta-Adrenergic Blocker
Adrenergic Agents
Adrenergic Antagonists
Anti-Arrhythmia Agents
Antihypertensive Agents
Cardiovascular Agents
Neurotransmitter Agents
Vasodilator Agents

ATC classes

C07A · BETA BLOCKING AGENTS
BETA BLOCKING AGENTS AND THIAZIDES
BETA BLOCKING AGENTS, OTHER COMBINATIONS

Cross-references

PubChem CID: 4946
ChEMBL: CHEMBL27
DrugBank: DB00571
ChEBI: CHEBI:8499
KEGG: D00483
RxNorm: 8787
Wikipedia: Propranolol
TTD: D04JEE
LINCS BRD: BRD-A10070317

Synonyms

Reported adverse events

Bradycardia
Hypersensitivity
Nausea
Oculomucocutaneous syndrome
Bronchospasm
Agranulocytosis
Systemic lupus erythematosus
Peyronie's disease
Stevens-Johnson syndrome
Hallucination
Purpura
Nightmare

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