PENICILLIN G

SynDRA canonical compound SYN0000120 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Mechanism of action	penicillin binding protein inhibitor
Indication	bacterial septicemia \| celluitis \| endocarditis \| meningitis \| pneumonia \| syphilis
Disease area	infectious disease

All known targets

Bact mrcA
Bact mrcA; Bact mrcB; Bact pbpC
ampC
bla; blaT-3; blaT-4;
dacA
dacB
dacC
ftsI
mrcA
mrcB
mrdA
pbpA

Mechanisms of action (all sources)

penicillin binding protein inhibitor
Binder
mrcA INHIBITOR
mrcB INHIBITOR
dacC INHIBITOR
mrdA INHIBITOR
ftsI INHIBITOR
dacA INHIBITOR
dacB INHIBITOR

Drug classes

Penicillin-class Antibacterial
Anti-Bacterial Agents
Anti-Infective Agents
Antineoplastic Agents

ATC classes

J01C · BETA-LACTAM ANTIBACTERIALS, PENICILLINS
S01A · ANTIINFECTIVES

Cross-references

PubChem CID: 5904
ChEMBL: CHEMBL29
DrugBank: DB01053
ChEBI: CHEBI:18208
KEGG: D01053
RxNorm: 7980
PDB: PNN
Wikipedia: Benzylpenicillin
TTD: D00QAR
LINCS BRD: BRD-K55191674

Synonyms

Reported adverse events

Hypersensitivity
Nausea
Phlebitis
Jarisch-Herxheimer reaction
Pseudomembranous colitis
Kounis syndrome

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