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HYDROCHLOROTHIAZIDE
SynDRA canonical compound SYN0000142 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC12A3 |
|---|
| Mechanism of action | Thiazide diuretic |
|---|
| Indication | congestive heart failure | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- SLC12A3
- CA1
- CA2
- CA4
- KCNMA1
- CA12
- CA9
- NAPEPLD
- SLC33A1
- ca1
Mechanisms of action (all sources)
- Thiazide diuretic
- SLC12A3 INHIBITOR
- Thiazide-sensitive sodium-chloride cotransporter inhibitor
- NAPEPLD BINDER
- SLC33A1 MODULATOR
Drug classes
- Thiazide Diuretic
- Antihypertensive Agents
- Cardiovascular Agents
- Diuretics
- Membrane Transport Modulators
- Natriuretic Agents
- Sodium Chloride Symporter Inhibitors
ATC classes
- C03A · LOW-CEILING DIURETICS, THIAZIDES
- DIURETICS AND POTASSIUM-SPARING AGENTS IN COMBINATION
- ACE INHIBITORS, COMBINATIONS
- ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
- OTHER AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
Cross-references
Synonyms
- hydrochlorothiazid
- hydrochlorthiazide
- hydrochlorzide
- Hidroclorotiazida
- Apresazide
- Carozide
- Chlorosulthiadil
- Copalia-hct
- Dafiro-hct
- Dihydrochlorurite
- Exforge-hct
- Hidrotiazida
- Hydrochlorothiaizide
- Hydrochlorothiazidum
- Hydrochlorthiazide
- Idrotiazide
- Imprida-hct
- Lotensin hct
- Megadiuril
- Newtolide
- Pantemon
- Rasilez-hct
- Servithiazid
- Unipres
- Vetidrex
- NSC-53477
- SU-5879
- Apo-hydro
- Esidrex
- Esidrix
- Hydro-d
- Hydrochlorothiazide component of accuretic
- Hydrochlorothiazide component of aldactazide
- Hydrochlorothiazide component of aldoril
- Hydrochlorothiazide component of amturnide
- Hydrochlorothiazide component of apresazide
- Hydrochlorothiazide component of apresoline-esidrix
- Hydrochlorothiazide component of avalide
Reported adverse events
- Hyperkalemia
- Hypersensitivity
- Hypotension
- Erythema multiforme
- Stevens-Johnson syndrome
- Pancreatitis
- Angioedema
- Anaphylactic reaction
- Vertigo
- Renal failure
- Cough
- Dizziness
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