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PYRIMETHAMINE
SynDRA canonical compound SYN0000147 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DHFR | DHFRP1 | HEXA | SLC47A1 | STAT3 |
|---|
| Mechanism of action | dihydrofolate reductase inhibitor |
|---|
| Indication | malaria |
|---|
| Disease area | infectious disease |
|---|
All known targets
- SLC47A1
- DHFR
- HEXA
- CHRM1
- dfrA17
- Slc47a2
- Slc47a1
- Slc22a1
- STAT3
- PTR1
- SLC22A1
- CYP2C9
Mechanisms of action (all sources)
- SLC47A1 INHIBITOR
- dihydrofolate reductase inhibitor
- FOLR1 MODULATOR
Drug classes
- Dihydrofolate Reductase Inhibitors
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Enzyme Inhibitors
- Folic Acid Antagonists
- Dihydrofolate Reductase Inhibitor Antimalarial
ATC classes
Cross-references
Synonyms
- chloridin
- chloridine
- diaminopyritamin
- pirimecidan
- pirimetamin
- pyrimethamin
- Pirimetamina
- Chloridine
- Pyrimethaminum
- GNF-PF-5586
- NSC-3061
- RP-4753
- TCMDC-123831
- TCMDC-125860
- WR-2978
- Daraprim
- Malacide
- Pyrimethamine component of fansidar
- Chloridin
- Chloridyn
- Darachlor
- Daraclor
- Darapram
- Daraprime
- Daraprin
- Diaminopyritamin
- Erbaprelina
- Ethylpyrimidine
- Khloridin
- Malacid
- Malocid
- Malocide
- Maloprim
- Pirimecidan
- Pirimetamin
- Primethamine
- Pyremethamine
- Pyrimethamin
Reported adverse events
- Vomiting
- Hypersensitivity
- Pulmonary eosinophilia
- Stevens-Johnson syndrome
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