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TOLRESTAT

SynDRA canonical compound SYN0000148 — structure-anchored drug synonym record

All known targets

• AKR1B1
• AKR1A1
• AKR1B10
• Akr1a1
• Akr1b1
• Akr1c21
• SIGMAR1

Mechanisms of action (all sources)

• Aldose reductase inhibitor
• AKR1B1 INHIBITOR
• SIGMAR1 BINDER

Drug classes

• Enzyme Inhibitors

ATC classes

• A10X · OTHER DRUGS USED IN DIABETES

Cross-references

• PubChem CID: 53359
• ChEMBL: CHEMBL436
• DrugBank: DB02383
• ChEBI: CHEBI:48549
• KEGG: D02323
• PDB: TOL
• Wikipedia: Tolrestat
• TTD: D0Q7QY
• LINCS BRD: BRD-K85693895

Synonyms

• tolrestatin
• lorestat
• alredase
• AY-27773
• AY-27,773
• Alderase
• Alredase
• SSR-125047
• Lorestat
• Tolrestatin
• Tolrestatum
• Tolrestatum [Latin]
• AY 27773
• 2-(6-Methoxy-N-methyl-5-(trifluoromethyl)naphthalene-1-carbothioamido)acetic acid
• UNII-0T93LG5NMK
• CHEMBL436
• 0T93LG5NMK
• CHEBI:48549
• LUBHDINQXIHVLS-UHFFFAOYSA-N
• N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]carbonothioyl}-N-methylglycine
• NCGC00183862-01
• N-(6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl)sarcosine
• N-{[6-methoxy-5-(trifluoromethyl)-1-naphthyl]carbonothioyl}-N-methylglycine
• N-[6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl]sarcosine
• RefChem:898551
• DTXCID3028760
• A10XA01
• TOL
• Alrestin
• Tolrestat [USAN:INN:BAN]
• Tolrestat?
• Alredase (TN)
• Tolrestat (Standard)
• TolrestatAY-27773
• TOLRESTAT [INN]
• TOLRESTAT [MI]
• Tolrestat (USAN/INN)
• TOLRESTAT [USAN]