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NORTRIPTYLINE
SynDRA canonical compound SYN0000177 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Tricyclic antidepressant |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A4
- SLC6A2
- KCNJ10
- ADRA1A
- ADRA2B
- CHRM3
- HTR2A
- HTR1A
- HRH1
- ADRA2C
- DRD2
- CYP2C19
Mechanisms of action (all sources)
- Tricyclic antidepressant
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
- ADRA1A ANTAGONIST
- KCNJ10 ANTAGONIST
- SLC6A4 MODULATOR
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Tricyclic Antidepressant
ATC classes
Cross-references
Synonyms
- nortryptyline
- demethylamitriptylin
- desitriptilina
- desmethylamitriptyline
- noramitriptyline
- nortriptyline hydrochloride
- nortriptyline HCl
- Nortriptilina
- Desitriptilina
- Lumbeck
- Noramitriptyline
- Nortrilen
- Sesaval
- NCI-169453
- NSC-757234
- Allegron
- Aventyl
- Motipress
- Motival
- Acetexa
- Altilev
- Ateben
- Avantyl
- Demethylamitriptylene
- Demethylamitriptyline
- Demethylamitryptyline
- Desitriptyline
- Desmethylamitriptylin
- Desmethylamitriptyline
- Noritren
- Nortriptylinum
- Nortryptiline
- Nortryptyline
- Pamelor
- Psychostyl
- Sensaval
- Vividyl
- AVENTYL HCL
Reported adverse events
- Jaundice
- Confusional state
- Dry mouth
- Nausea
- Hypotension
- Brugada syndrome
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