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BUSPIRONE
SynDRA canonical compound SYN0000251 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | HTR1A |
| Mechanism of action | Serotonin receptor agonist |
| Indication | generalized anxiety disorder (GAD) |
| Disease area | neurology/psychiatry |
All known targets
- HTR1A
- DRD2
- HTR2A
- HTR2C
- HTR7
- Htr1a
- Htr1b
- Htr1d
- Htr1f
- Htr2a
- Htr2b
- Htr2c
Mechanisms of action (all sources)
- Serotonin receptor agonist
- HTR1A PARTIAL AGONIST
- Serotonin 1a (5-HT1a) receptor partial agonist
- HTR1A AGONIST
Drug classes
- Anti-Anxiety Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Neurotransmitter Agents
- Psychotropic Drugs
- Serotonin Agents
- Serotonin Receptor Agonists
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- buspin
- buspirone hydrochloride
- buspirone HCl
- Buspirona
- Gen-buspirone
- BCI-024
- Ansial
- Ansiced
- Anxiron
- Axoren
- Bespar
- Buspironum
- Buspisal
- Ansial (TN)
- Ansiced (TN)
- Anxiron (TN)
- Axoren (TN)
- Bespar (TN)
- BuSpar (TN)
- Buspimen (TN)
- Buspinol (TN)
- Buspiron (TN)
- Buspirona [INN-Spanish]
- Buspirone (INN)
- Buspirone [INN:BAN]
- Buspirone-MDTS
- Buspironum [INN-Latin]
- Buspisal (TN)
- Gen-Buspirone
- Narol (TN)
- Sorbon (TN)
- Spamilan (TN)
- Spitomin (TN)
- Gen-Buspirone (TN)
- MJ-9022-1
- N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide
- 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione
- 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
Reported adverse events
- Dizziness
- Anger
- Depression
- Hostility
- Insomnia
- Nausea
- Palpitations
- Constipation
- Fatigue
- Headache
- Tremor
- Nervousness
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