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PODOFILOX
SynDRA canonical compound SYN0000318 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | IGF1R | TOP2A | TUBA4A | TUBB |
| Mechanism of action | microtubule inhibitor | tubulin polymerization inhibitor |
| Indication | genital warts |
| Disease area | infectious disease |
All known targets
- TUBB
- TUBA4A
- CYP2C19
- TUBA3E
- TUBB6
- TUBB4B
- TUBB4A
- TUBB3
- TUBB2B
- TUBB2A
- TUBB1
- TUBA3C
Mechanisms of action (all sources)
- microtubule inhibitor
- tubulin polymerization inhibitor
- Modulator
Drug classes
- Antimitotic Agents
- Antineoplastic Agents
- Antineoplastic Agents, Phytogenic
- Dermatologic Agents
- Keratolytic Agents
- Tubulin Modulators
ATC classes
- D06B · CHEMOTHERAPEUTICS FOR TOPICAL USE
Cross-references
Synonyms
- podophyllotoxin
- condyline
- Podophyllotoxin
- NSC-24818
- Condyline
- Condylox
- Warticon
- Wartec
- Podophyllotoxin 7
- Podophyllinic acid lactone
- (-)-Podophyllotoxin
- Podofilox [USAN]
- CCRIS 565
- UNII-L36H50F353
- Podophyllotoxin, 95%
- HSDB 7238
- NSC24818
- CHEMBL61
- EINECS 208-250-4
- NSC 24818
- (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
- MLS000069495
- AI3-50456
- CHEBI:50305
- Podofilox (USAN)
- L36H50F353
- Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one,
- BRD-K47869605
- Podophyllum
- MFCD00075290
- (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
- (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
- (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one
- NCGC00022001-05
- Podofilm
- SMR000059121
- (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one
- (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
Reported adverse events
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