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ISONIAZID
SynDRA canonical compound SYN0000326 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP3A4 |
|---|
| Mechanism of action | Enoyl-acyl-carrier protein reductase inhibitor |
|---|
| Indication | tuberculosis |
|---|
| Disease area | infectious disease |
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All known targets
- CYP3A4
- CYP1A2
- CYP2C19
- CYP2C8
- CYP2E1
- Bact inhA
- CYP3A5
- MPO
- folA
- inhA
- katG
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- Enoyl-acyl-carrier protein reductase inhibitor
- FABI inhibitor
- Inhibitor
- INHA INHIBITOR
Drug classes
- Antimycobacterial
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antimetabolites
- Antitubercular Agents
- Fatty Acid Synthesis Inhibitors
- Hypolipidemic Agents
ATC classes
- J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS
Cross-references
Synonyms
- 4-Pyridinecarboxylic hydrazide
- armazid
- isoniazide
- isonicotinohydrazide
- Isoniazide
- Isoniazida
- Armazid
- Armazide
- Atcotibine
- Cedin
- Cotinazin
- Dianicotyl
- Eralon
- Ertuban
- Hidrasonil
- Hydrazid
- Ipcazide
- Iscotin
- Isidrina
- Isobicina
- Isoniazidum
- Isonicotan
- Mybasan
- Neumandin
- Teebaconin
- Tisiodrazida
- NSC-9659
- Dow-isoniazid
- Hyzyd
- Inh
- Isoniazid component of rifamate
- Isoniazid component of rifater
- Laniazid
- Nicotibine
- Nydrazid
- Rimifon
- Stanozide
- Abdizide
Reported adverse events
- Nausea
- Agranulocytosis
- Hypersensitivity
- Cerebellar syndrome
- Stevens-Johnson syndrome
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