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KETOROLAC
SynDRA canonical compound SYN0000332 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | pain relief |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- PTGS1
- PTGS2
- Akr1b1
- Fabp1
- PAK1
- PTGS1; PTGS2
- Ptgds
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- Inhibitor
Drug classes
- Cyclooxygenase Inhibitors
- Nonsteroidal Anti-inflammatory Drug
- Cyclooxygenase Inhibitor
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- S01B · ANTIINFLAMMATORY AGENTS
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
- MYDRIATICS AND CYCLOPLEGICS
Cross-references
Synonyms
- ketorolac tromethamine
- ketorolac trometamol
- trometamol ketorolac
- (+/-)-Ketorolac
- keromin
- Ketorolaco
- Ketoralac
- Ketorolacum
- Macril
- Ketorolaco [Spanish]
- Ketorolacum [Latin]
- RS-37619
- Acular (TN)
- Ketorolac (INN)
- Ketorolac [INN:BAN]
- Toradol (TN)
- (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- (+-)-Ketorolac
- (+-)-isomer
- (+/-)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
- 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
- 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- 5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
- 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- YZI5105V0L
- rac Ketorolac
- CHEBI:6129
- 5-(benzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
- RefChem:55433
- DTXCID503189
- M01AB15
- S01BC05
- MFCD00864281
- (1RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- RS37619
- KETOROLAC [INN]
- NCGC00185990-01
Reported adverse events
- Bleeding
- GI bleed
- Ulceration
- Elderly
- Crohn's disease
- Stevens-Johnson syndrome
- Rash
- Hypersensitivity
- Hypertension
- Headache
- Nausea
- Constipation
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