← SynDRA
GLYBURIDE
SynDRA canonical compound SYN0000363 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ABCC8 |
|---|
| Mechanism of action | Insulin secretagogue |
|---|
| Indication | diabetes mellitus | hyperglycemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ABCC8
- KCNJ11
- CFTR
- KCNJ8
- ABCC9
- SLCO2B1
- ABCB11
- KCNJ5
- ABCA1
- TRPA1
- PPARG
- Nlrp3
Mechanisms of action (all sources)
- Sulfonylurea
- ATP channel blocker
- Insulin secretagogue
- KCNJ11 BLOCKER
- Sulfonylurea receptor 1, Kir6.2 blocker
- ABCC8 BLOCKER
- CFTR PORE BLOCKER
- KCNJ8 MODULATOR
- KCNJ11 MODULATOR
- SLCO2B1 INHIBITOR
- ABCC8 MODULATOR
Drug classes
- Hypoglycemic Agents
- Sulfonylurea
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- glibenclamide
- glicuformine
- GLIBENCLAMIDE
- GLIBENCLAMIDA
- CIRARA
- GLIBENCLAMIDUM
- GLYBENCLAMIDE
- Amglidia
- Calabren
- Daonil
- Diabeta
- Diabetamide 2.5
- Diabetamide 5
- Euglucon
- Gliken
- GLYBURIDE (GLIBENCLAMIDE)
- Glyburide (micronized)
- Glyburide component of glucovance
- GLYBURIDE10238-21-8
- Glynase
- HB-419
- Lederglib
- Libanil
- Malix
- Micronase
- NSC-759618
- Semi-daonil
- U-26,45
- U-26,452
- U-26452
- Glibenclamide
- Abbenclamide
- Adiab
- Azuglucon
- Bastiverit
- Benclamin
- Betanase
- Cytagon
Reported adverse events
- Lactic acid
- Lactic acidosis
- Leukopenia
- Porphyria
- Headache
- Nausea
- Dizziness
- Abdominal pain
- Angioedema
- Vitamin B12
- Vitamin B1
Look up GLYBURIDE in the interactive SynDRA portal →