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THIORIDAZINE
SynDRA canonical compound SYN0000380 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR2C |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | psychosis |
|---|
| Disease area | Neurology |
|---|
All known targets
- DRD2
- HTR2A
- HTR2C
- DRD1
- DRD5
- HTR6
- HTR7
- DRD3
- DRD4
- HTR1A
- HRH1
- MALT1
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- DRD2 ANTAGONIST
- D2-like dopamine receptor antagonist
- DRD3 ANTAGONIST
- DRD4 ANTAGONIST
- HTR1A ANTAGONIST
- HTR6 INVERSE AGONIST
- HTR7 INVERSE AGONIST
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
- Phenothiazine
ATC classes
Cross-references
Synonyms
- thioridazin
- dl-Thioridazine
- malloryl
- meleril
- thioridazine hydrochloride
- thioridazine HCl
- Tioridazina
- Dl-thioridazine
- Mellerette
- Novoridazine
- Sonapax
- Thioridazine prolongatum
- Thioril
- TP-21
- Mellaril-s
- Melleril
- Rideril
- Aldazine
- Mallorol
- Malloryl
- Meleril
- Mellaril
- Mellarit
- Mellerets
- Melleretten
- Melleryl
- Metlaril
- Orsanil
- Ridazine
- Stalleril
- Thioridazin
- Thioridazinum
- Thioxidazine
- Tioridazin
- Thioridazine Hcl
- Thioridazine Hcl Intensol
- Thoridazine hydrochloride
- Dl-Thioridazine
Reported adverse events
- Torsades de pointes
- Agranulocytosis
- Akathisia
- Dyskinesia
- Erythema
- Hepatotoxicity
- Hyperpyrexia
- Hypotension
- Jaundice
- Miosis
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