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IRINOTECAN

SynDRA canonical compound SYN0000382 — structure-anchored drug synonym record

All known targets

• TOP1
• ABCB1
• ABCC1
• TOP1MT
• SLC47A2
• SLC47A1
• SLC22A3
• SLC22A2
• SLC22A1
• MMP1
• CYP3A5
• CHRM4

Mechanisms of action (all sources)

• topoisomerase inhibitor
• TOP1 INHIBITOR
• DNA topoisomerase I inhibitor
• TOP1 MODULATOR

Drug classes

• Topoisomerase Inhibitors
• Antineoplastic Agents
• Enzyme Inhibitors
• Topoisomerase I Inhibitors
• Topoisomerase Inhibitor

ATC classes

• L01C · PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS

Cross-references

• PubChem CID: 60838
• ChEMBL: CHEMBL541887
• DrugBank: DB00762
• ChEBI: CHEBI:80630
• KEGG: D01061
• RxNorm: 51499
• PDB: CP0
• Wikipedia: Irinotecan
• TTD: D07HOB
• LINCS BRD: BRD-K08547377

Synonyms

• irinotecan liposome injection
• onivyde
• irinotecan liposome
• irinotecan hydrochloride
• irinotecan hydrochloride hydrate
• irinotecan hydrochloride trihydrate
• irinotecan HCl
• Biotecan
• Irinophore c
• NSC-728073
• Camptosar
• Irinotecanum
• IRINOTECAN HYDROCHLORIDE Trihydrate
• Irinotecan Hcl
• Irinotecan hydrochloride
• CP0
• Biotecan (TN)
• Campto (TN)
• Camptosar (TN)
• Irinotecan (INN)
• Irinotecan [INN:BAN]
• Irinotecanum [INN-Latin]
• IRINOTECAN, CPT-11
• Camptosar, Campto, CPT-11, Irinotecan
• (+)-Irinotecan
• (4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
• (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
• Irinotecan (TOPO1 inhibitor)
• Onivyde
• Irinotecan lactone
• Campto
• Irinophore C
• Irinotecan mylan
• CPT-11
• Irinotecan Free base
• (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate
• HSDB 7607
• CHEMBL481