← SynDRA

ADEFOVIR

SynDRA canonical compound SYN0000394 — structure-anchored drug synonym record

All known targets

• HSV UL30

Mechanisms of action (all sources)

• DNA polymerase inhibitor
• Inhibitor

Cross-references

• PubChem CID: 60172
• ChEMBL: CHEMBL484
• DrugBank: DB13868
• ChEBI: 2469
• KEGG: C11277
• RxNorm: 16521
• PDB: 5HG
• Wikipedia: Adefovir
• TTD: D00UUM

Synonyms

• GS-0393
• GS0393
• PMEA
• ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid
• 9-(2-Phosphonylmethoxyethyl)adenine
• GS 0393
• GS 393
• 9-(2-(Phosphonomethoxy)ethyl)adenine
• N-(2-Phosphonylmethoxyethyl)adenine
• DRG-0156
• UNII-6GQP90I798
• C8H12N5O4P
• HSDB 8079
• CHEMBL484
• 2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid
• BRN 3561094
• {[2-(6-Amino-9h-Purin-9-Yl)ethoxy]methyl}phosphonic Acid
• N-(2-Phophonomethoxyethyl-2,6-diaminopurine)
• Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-
• 6GQP90I798
• Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-
• 9-(2-phosphonomethoxyethyl)adenine
• 9-[2-(phosphonomethoxy)ethyl]adenine
• CHEBI:2469
• DTXCID4026214
• [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic Acid
• 9-[2-phosphonomethoxyethyl]adenine
• 9-PMEA
• Adefovirum
• Phosphonylmethoxyethyl-a
• RefChem:56259
• J05AF08
• MFCD00866943
• (2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic acid
• [2-(6-amino-9H-purin-9-yl)ethoxy]methylphosphonic acid
• NCGC00160539-01
• Adefovir [USAN:INN:BAN]
• SUPKOOSCJHTBAH-UHFFFAOYSA-N

Reported adverse events

• Lactic acidosis
• HIV infection
• Lactic acid
• Fanconi syndrome
• Headache
• Asthenia
• Dyspepsia
• Flatulence
• Hepatitis
• Nausea