LIDOCAINE

SynDRA canonical compound SYN0000422 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	SCN10A
Mechanism of action	Histamine receptor agonist
Indication	eczema \| hemorrhage \| itching
Disease area	dermatology \| hematology \| neurology/psychiatry

All known targets

SCN5A
SCN10A
SCN9A
SCN3A
SCN11A
SCN2A
SCN4A
SCN7A
Scn3a
Scn2a
Scn1a
Scn10a

Mechanisms of action (all sources)

Histamine receptor agonist
SCN1A BLOCKER
Sodium channel alpha subunit blocker
SCN5A BLOCKER
SCN4A BLOCKER
SCN7A BLOCKER
SCN2A BLOCKER
SCN9A BLOCKER
SCN3A BLOCKER
SCN11A BLOCKER
SCN8A BLOCKER
SCN10A BLOCKER

Drug classes

Antiarrhythmic
Anesthetics
Anesthetics, Local
Anti-Arrhythmia Agents
Cardiovascular Agents
Central Nervous System Agents
Central Nervous System Depressants
Membrane Transport Modulators
Peripheral Nervous System Agents
Sensory System Agents
Sodium Channel Blockers
Voltage-Gated Sodium Channel Blockers

ATC classes

R02A · THROAT PREPARATIONS
D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
N01B · ANESTHETICS, LOCAL
S01H · LOCAL ANESTHETICS
C01B · ANTIARRHYTHMICS, CLASS I AND III
S02D · OTHER OTOLOGICALS
C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

Cross-references

PubChem CID: 3676
ChEMBL: CHEMBL79
DrugBank: DB00281
ChEBI: CHEBI:6456
KEGG: D00358
RxNorm: 6387
PDB: LQZ
Wikipedia: Lidocaine
TTD: D0X4RN
LINCS BRD: BRD-K52662033

Synonyms

Reported adverse events

Hypersensitivity
Hypersensitivity reaction
Asthenia
Bradycardia
Adverse reaction
Nausea
Vomiting
Tremor
Vision blurred
Hypertension
Chondrolysis
Injection

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