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METOCLOPRAMIDE
SynDRA canonical compound SYN0000458 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | HTR4 |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | gastroparesis | nausea | vomiting |
|---|
| Disease area | gastroenterology |
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All known targets
- DRD2
- HTR3A
- HTR4
- CHRM1
- HTR3B
- Htr3a
- Htr2c
- Htr2b
- Htr3b
- Htr2a
- HTR3C
- Htr1f
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR3A ANTAGONIST
- Serotonin 3a (5-HT3a) receptor antagonist
- HTR4 AGONIST
- Serotonin 4 (5-HT4) receptor agonist
- HTR3A|HTR3B ANTAGONIST
Drug classes
- Antiemetics
- Central Nervous System Agents
- Dopamine Agents
- Dopamine Antagonists
- Dopamine D2 Receptor Antagonists
- Gastrointestinal Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Dopamine D2 Antagonists
- Dopamine-2 Receptor Antagonist
ATC classes
Cross-references
Synonyms
- metoclopramide hydrochloride
- metochlopramide
- methochlopramide
- metoclopramide hydrochloride hydrate
- metoclopramide monohydrochloride
- metoclopramide HCl
- AHR-3070-C
- metaclopramide
- Metoclopramida
- Clopra-"yellow"
- Elieten
- Methoxyclopramide
- Terperan
- Cerucal
- Clopra
- Clopromate
- Duraclamid
- Emetid
- Emitasol
- Emperal
- Eucil
- Gastrese
- Gastrobid
- Gastromax
- Gastronerton
- Gastrosil
- Gastrotablinen
- Gastrotem
- Imperan
- Maxeran
- Maxolon
- Meclopran
- Metaclopramide
- Metaclopromide
- Metamide
- Methochlopramide
- Methoclopramide
- Metochlopramide
Reported adverse events
- Tardive dyskinesia
- Fluid retention
- Insomnia
- Restlessness
- Depression
- Hallucination
- Hypersensitivity
- Hypertension
- Agranulocytosis
- Bronchospasm
- Hepatotoxicity
- Neuroleptic malignant syndrome
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