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ZILEUTON
SynDRA canonical compound SYN0000501 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ALOX5 |
|---|
| Mechanism of action | Lipoxygenase inhibitor |
|---|
| Indication | asthma |
|---|
| Disease area | pulmonary |
|---|
All known targets
- ALOX5
- ALOX15
- ALOX5AP
- Alox5
- CYSLTR2
- EPHX2
- LTA4H
- LTB4R
- PTGES
Mechanisms of action (all sources)
- Leukotriene inhibitor
- Lipoxygenase inhibitor
- ALOX5 INHIBITOR
- Arachidonate 5-lipoxygenase inhibitor
- leukotriene synthesis inhibitor
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Enzyme Inhibitors
- Hormone Antagonists
- Leukotriene Antagonists
- Lipoxygenase Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
- 5-Lipoxygenase Inhibitors
Cross-references
Synonyms
- leutrol
- A 64077
- A-64077
- ABBOTT-64077
- NSC-730712
- NSC-759277
- Zyflo
- Zyflo cr
- Leutrol
- Zileutonum
- Ziluton
- Abbott brand of zileuton
- Zyflo CR
- Zyflo Filmtab
- Abbot 64077
- ABT-077
- CTI-02
- ZYFLO (TN)
- ZYFLO, Zileuton
- Zileutonum [INN-Latin]
- Zileuton (USP/INN)
- Zileuton [USAN:INN:BAN]
- N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
- N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
- (+-)-1-(1-Benzo(b)thien-2-ylethyl)-1-hydroxyurea
- (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
- (+/-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
- 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
- 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
- NSC 730712
- zileuton (usp-rs)
- Abbott 64077
- zileuton (usp monograph)
- NSC 759277
- Urea, N-(1-benzo(b)thien-2-ylethyl)-N-hydroxy-, (+-)-
- V1L22WVE2S
- DTXCID003752
- CHEBI:10112
Reported adverse events
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