MECLOFENAMIC ACID

SynDRA canonical compound SYN0000562 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	PTGS2
Mechanism of action	Prostanoid receptor antagonist
Indication	joint pain \| muscle pain \| primary dysmenorrhea (PD) \| rheumatoid arthritis
Disease area	endocrinology \| neurology/psychiatry \| rheumatology

All known targets

PTGS2
PTGS1
ALOX5
TRPM4
CNR1
AKR1C1
MAPK1
Ptgs2
Ptgs1
PTGS1; PTGS2
KCNQ2
KCNQ3

Mechanisms of action (all sources)

Cyclooxygenase inhibitor
Prostanoid receptor antagonist
ALOX5 INHIBITOR
Arachidonate 5-lipoxygenase inhibitor
PTGS2 INHIBITOR
PTGS1 INHIBITOR
TRPM4 MODULATOR
CNR1 ANTAGONIST
Inhibitor

Drug classes

Analgesics
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Anti-Inflammatory Agents, Non-Steroidal
Antirheumatic Agents
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Peripheral Nervous System Agents
Sensory System Agents

ATC classes

M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN

Cross-references

PubChem CID: 4037
ChEMBL: CHEMBL509
DrugBank: DB00939
ChEBI: CHEBI:6710
KEGG: D00169
RxNorm: 6678
PDB: JMS
TTD: D08IFL
LINCS BRD: BRD-K50398167

Synonyms

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