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CARMUSTINE

SynDRA canonical compound SYN0000578 — structure-anchored drug synonym record

All known targets

• GSR
• TXNRD1
• TXNRD2

Mechanisms of action (all sources)

• DNA inhibitor
• DNA alkylating agent
• GSR INHIBITOR
• Glutathione reductase inhibitor

Drug classes

• Alkylating Activity
• Alkylating Drug
• Alkylating Agents
• Antineoplastic Agents
• Antineoplastic Agents, Alkylating
• Noxae

ATC classes

• L01A · ALKYLATING AGENTS

Cross-references

• PubChem CID: 2578
• ChEMBL: CHEMBL513
• DrugBank: DB00262
• ChEBI: CHEBI:3423
• KEGG: D00254
• RxNorm: 2105
• Wikipedia: Carmustine
• TTD: D01OXI
• LINCS BRD: BRD-K36234266

Synonyms

• becenun
• carmubris
• carmustin
• nitrumon
• Carmustina
• Becenun
• Bischloroethyl nitrosourea
• Camustine
• Carmubris
• BCNU
• DTI-015
• FDA-0345
• NSC-409962
• SK-27702
• SRI-1720
• Bicnu
• Carmustine medac (previously carmustine obvius)
• Carmustine obvius
• Gliadel
• DTI 015
• 1,3-Bis(2-chloroethyl)-1-nitrosourea
• Carmustin
• Nitrumon
• BiCNU
• Bi CNU
• Carmustinum
• Bischlorethylnitrosurea
• Bischlorethylnitrosourea
• Becenum
• N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA
• Bis(2-chloroethyl)nitrosourea
• Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
• Gliadel Wafer
• FDA 0345
• Bischloroethylnitrosourea
• SRI 1720
• 1,3-Bis(2-chloroethyl)nitrosourea
• BiCNU (TN)

Reported adverse events

• Myelosuppression
• Pulmonary toxicity
• Se
• Nausea
• Headache
• Infection
• Opportunistic infection
• Tachycardia
• Burning sensation
• Carcinogenicity
• Hepatotoxicity
• Neoplasm