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LOMUSTINE
SynDRA canonical compound SYN0000581 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | DNA synthesis inhibitor |
|---|
| Indication | brain tumors | Hodgkin's lymphoma |
|---|
| Disease area | hematologic malignancy | oncology |
|---|
Mechanisms of action (all sources)
Drug classes
- Alkylating Activity
- Alkylating Drug
- Alkylating Agents
- Antineoplastic Agents
- Antineoplastic Agents, Alkylating
- Noxae
ATC classes
Cross-references
Synonyms
- belustine
- chloroethylcyclohexylnitrosourea
- lomustin
- Lomustina
- CCN-U
- Ccnu
- NSC-79037
- Ceenu
- Gleostine
- Belustine
- CCNU
- CINU
- Cecenu
- CeeNU
- Chloroethylcyclohexylnitrosourea
- Lomustinum
- Bristol-Myers Squibb Brand of Lomustine
- CCNU [Chloroethyl nitrosoureas]
- Cyclohexyl chloroethyl nitrosourea
- Lomustine medac Brand
- Medac Brand of Lomustine
- Rhone-Poulenc Rorer Brand of Lomustine
- OR5087
- RB 1509
- SRI 2200
- CeeNU (TN)
- Lomustina [INN-Spanish]
- Lomustinum [INN-Latin]
- NPFAPI-06
- CeeNU, CCNU, Lomustine
- Lomustine (USAN/INN)
- Lomustine [USAN:BAN:INN]
- N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea
- (Chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea
- (Cloro-2-etil)-1-cicloesil-3-nitrosourea
- (Cloro-2-etil)-1-cicloesil-3-nitrosourea [Italian];1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
- 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea [Chloroethyl nitrosoureas]
- 1-(2-Chloroethyl)-3-cyclohexylnitrosourea
Reported adverse events
- Myelosuppression
- Thrombocytopenia
- Pulmonary toxicity
- Gastrointestinal disorder
- Hepatotoxicity
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