GAMMA-AMINOBUTYRIC ACID

SynDRA canonical compound SYN0000582 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	GABBR1 \| GABBR2 \| GABRA1 \| GABRA2 \| GABRA3 \| GABRA5 \| GABRB2 \| GABRG2 \| GATM \| KCTD12 \| KCTD16 \| KCTD8 \| SLC6A1
Mechanism of action	benzodiazepine receptor agonist

All known targets

SLC6A1
GABRB2
GABRA1
GABRA2
GABRA3
GABRA5
GABRG2
SLC6A11
SLC6A12
KCTD16
KCTD8
GABBR1

Mechanisms of action (all sources)

GABBR1|GABBR2|KCTD8|KCTD12|KCTD16 FULL AGONIST
benzodiazepine receptor agonist
GABRG2 INHIBITOR
Inhibitor
SLC6A11 INHIBITOR
GABRA2 INHIBITOR
GABRA3 INHIBITOR
GABRB2 INHIBITOR
GABRA1 INHIBITOR
GABRA5 INHIBITOR
SLC6A1 INHIBITOR
ITGA4 BINDER

Drug classes

GABA Agents
Neurotransmitter Agents

ATC classes

N03A · ANTIEPILEPTICS

Cross-references

PubChem CID: 119
ChEMBL: CHEMBL96
DrugBank: DB02530
ChEBI: CHEBI:16865
KEGG: C00334
RxNorm: 4617
PDB: ABU
Wikipedia: GABA
TTD: D04QAC
LINCS BRD: BRD-K77245796

Synonyms

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