CYPROHEPTADINE

SynDRA canonical compound SYN0000590 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	HRH1
Mechanism of action	Histamine receptor antagonist
Indication	allergic rhinitis \| conjunctivitis \| dermatographism \| urticaria \| vasomotor rhinitis
Disease area	allergy \| dermatology \| ophthalmology \| otolaryngology

All known targets

HRH1
HTR6
ADRA1B
ADRA1D
ADRA1A
HTR7
CHRM3
CHRM2
CHRM1
HTR2C
HTR2B
HTR2A

Mechanisms of action (all sources)

Histamine receptor antagonist
HRH1 ANTAGONIST
Histamine H1 receptor antagonist
HTR6 ANTAGONIST
HTR7 ANTAGONIST
ADRA1A ANTAGONIST
ADRA1B ANTAGONIST
ADRA1D ANTAGONIST

Drug classes

Anti-Allergic Agents
Antipruritics
Dermatologic Agents
Gastrointestinal Agents
Histamine Agents
Histamine Antagonists
Histamine H1 Antagonists
Neurotransmitter Agents
Serotonin Agents
Serotonin Antagonists

ATC classes

R06A · ANTIHISTAMINES FOR SYSTEMIC USE

Cross-references

PubChem CID: 2913
ChEMBL: CHEMBL516
DrugBank: DB00434
ChEBI: CHEBI:4046
KEGG: D02234
RxNorm: 3013
PDB: C7H
Wikipedia: Cyproheptadine
TTD: D00TLN
LINCS BRD: BRD-K28143534

Synonyms

periactin
cyproheptadine hydrochloride
cycloheptadine
periactinol
cyproheptadine HCl
Ciproheptadina
Ciprovit
Cypoheptadine
Cyproheptadiene
Cyproheptadinum
Dihexazin
Dronactin
Eiproheptadine
Periactin
Periactine
Periactinol
Viternum
Cyproheptadine Hcl
MK 141
Ciproheptadina [INN-Spanish]
Ciprovit (TN)
Cyproheptadine (INN)
Cyproheptadine [INN:BAN]
Cyproheptadinum [INN-Latin]
Dibenzosuberonone/Cyproheptadine
Periactin (TN)
1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
Peritol
CHEMBL516
Piperidine, 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-

Reported adverse events

Fatigue
Sedation
Hypotension
Cholestasis

Look up CYPROHEPTADINE in the interactive SynDRA portal →