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FLUCONAZOLE
SynDRA canonical compound SYN0000748 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP51A1 |
|---|
| Mechanism of action | Sterol demethylase inhibitor |
|---|
| Indication | esophageal candidiasis | meningitis |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP51A1
- CYP2C19
- CYP2C9
- CYP3A4
- CYP3A5
- CYP3A7
- CYP51
- Candi ERG11
- ERG11
- cyp121
- cyp51
- cyp51B
Mechanisms of action (all sources)
- Sterol demethylase inhibitor
- Modulator
- ERG11 INHIBITOR
Drug classes
- Azole Antifungal
- Cytochrome P450 2C19 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- Cytochrome P450 2C9 Inhibitors
- 14-alpha Demethylase Inhibitors
- Anti-Infective Agents
- Antifungal Agents
- Cytochrome P-450 CYP2C19 Inhibitors
- Cytochrome P-450 CYP2C9 Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Hormone Antagonists
ATC classes
- J02A · ANTIMYCOTICS FOR SYSTEMIC USE
- D01A · ANTIFUNGALS FOR TOPICAL USE
- COMBINATIONS OF ANTIBACTERIALS
Cross-references
Synonyms
- difluconazole
- flunazol
- diflucan
- Fluconazol
- Alkanazole
- Difluconazole
- Fluconazoli
- Zoltec
- BAYT-006267
- BAYT006267
- NSC-758661
- UK-49,858
- UK-49858
- Canesten oral
- Diflucan
- Diflucan one
- Triflucan
- Afungil
- Alflucoz
- Baten
- Beagyne
- Biocanol
- Biozolene
- Canzol
- Cryptal
- Diflazon
- Dimycon
- Elazor
- FCZ
- FLCZ
- Flucazol
- FlucoLich
- Flucobeta
- Fluconazolum
- Flucostat
- Flukezol
- Flunazul
- Flunizol
Reported adverse events
- Seizure
- Stevens-Johnson syndrome
- Nausea
- Vomiting
- Cholestasis
- Insomnia
- Abdominal pain
- Asthenia
- Leukopenia
- Myalgia
- Dyspepsia
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