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ALVOCIDIB

SynDRA canonical compound SYN0000765 — structure-anchored drug synonym record

All known targets

• CDK9
• CDK1
• CDK2
• CDK4
• CDK6
• CDK7
• PYGM
• CDK5
• CDK8
• EGFR
• BCL2
• BIRC5

Mechanisms of action (all sources)

• cyclin-dependent kinase inhibitor
• CDK2 INHIBITOR
• Cyclin-dependent kinase 2 inhibitor
• CDK4/6 inhibitor
• Cyclin-dependent kinase 4 inhibitor
• Cyclin-dependent kinase 6 inhibitor
• CDK9 INHIBITOR
• Cyclin-dependent kinase 9 inhibitor
• CDK1 INHIBITOR
• Cyclin-dependent kinase 1 inhibitor
• CDK7 INHIBITOR
• Cyclin-dependent kinase 7 inhibitor

Drug classes

• Antineoplastic Agents
• Growth Inhibitors
• Protein Kinase Inhibitors

Cross-references

• PubChem CID: 5287969
• ChEMBL: CHEMBL428690
• DrugBank: DB03496
• ChEBI: 47344
• KEGG: D09868
• PDB: CPB
• Wikipedia: Alvocidib
• TTD: D0LF1U
• LINCS BRD: BRD-K87909389

Synonyms

• Flavopiridol
• Alvocidib freebase
• HL 275
• HMR 1275
• L-86-8275
• L-868275
• L86-8275
• MDL 107,826A
• MDL-107826A
• NSC-649890
• FLAVO
• Alvocidib [INN]
• Flavopiridol hydrochloride
• HMR-1275
• HMR-1275, Alvocidib, L868275, Flavopiridol
• (-)-cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one
• 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE
• 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
• Flavopiridol (Alvocidib)
• HMR-1274
• L 86-8275
• 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
• CHEMBL428690
• 45AD6X575G
• 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
• NSC 649890 HCl
• 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one
• Flavoperidol
• 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-
• Alvocidib [USAN]
• L868275
• Alvocidib [USAN:INN]
• alvocidibum
• UNII-45AD6X575G
• CCRIS 9399
• 4H-1-BENZOPYRAN-4-ONE, 2-(2-CHLOROPHENYL)-5,7-DIHYDROXY-8-((3S,4R)-3-HYDROXY-1-METHYL-4-PIPERIDINYL)-
• (-)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one
• NSC649890