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COLCHICINE
SynDRA canonical compound SYN0000772 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | TUBB1 |
| Mechanism of action | Microtubule inhibitor |
| Indication | fever | gout |
| Disease area | endocrinology | rheumatology |
All known targets
- TUBB
- TUBB4B
- GLRA1
- GLRA2
- TUBA1A
- TUBB2B
- TUBB1
- ABCB1
- TUBA4A
- TUBB6
- TUBB4A
- TUBB3
Mechanisms of action (all sources)
Drug classes
- P-Glycoprotein Interactions
- Antimitotic Agents
- Antirheumatic Agents
- Gout Suppressants
- Tubulin Modulators
- Cytochrome P450 3A4 Inhibitors
- Alkaloid
ATC classes
- M04A · ANTIGOUT PREPARATIONS
Cross-references
Synonyms
- colchisol
- colcin
- (-)-colchicine
- Colchcine
- Colchicinum
- Colchineos
- Colchisol
- Lodoco
- NSC-757
- Colchicine component of col-probenecid
- Colchicine component of colbenemid
- Colchicine component of mitigare
- Colchicine component of proben-c
- Colcrys
- Gloperba
- Mitigare
- Colchicin
- Colchicina
- Colchysat
- Colcin
- Colsaloid
- Colstat
- Condylon
- Goutnil
- Kolkicin
- LOC
- Binds to tubulin
- Colchicin [German]
- Colchicina [Italian]
- Colchicine [JAN]
- Inhibits microtubular assembly
- Spindle poison
- C 9754
- Colchicine (TN)
- Colchicine, Colchicum autumnale
- MPC-004
- N-Acetyl trimethylcolchicinic acid methylether
- Colchicine (JP15/USP)
Reported adverse events
- Nausea
- Vomiting
- Fatigue
- Headache
- Prophylaxis
- Hypersensitivity
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