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MEXILETINE

SynDRA canonical compound SYN0000824 — structure-anchored drug synonym record

All known targets

• SCN5A
• SCN4A
• SCN9A
• KCNK3
• SCN10A
• SCN1A
• SCN2A
• CYP2B6
• SCN3B
• Scn1a
• Scn10a
• SLC22A2

Mechanisms of action (all sources)

• Sodium channel blocker
• SCN1A BLOCKER
• Sodium channel alpha subunit blocker
• SCN5A BLOCKER
• SCN4A BLOCKER
• SCN7A BLOCKER
• SCN2A BLOCKER
• SCN9A BLOCKER
• SCN3A BLOCKER
• SCN11A BLOCKER
• SCN8A BLOCKER
• SCN10A BLOCKER

Drug classes

• Antiarrhythmic
• Anti-Arrhythmia Agents
• Cardiovascular Agents
• Membrane Transport Modulators
• Sodium Channel Blockers
• Voltage-Gated Sodium Channel Blockers

ATC classes

• C01B · ANTIARRHYTHMICS, CLASS I AND III

Cross-references

• PubChem CID: 4178
• ChEMBL: CHEMBL146855
• DrugBank: DB00379
• ChEBI: CHEBI:6916
• KEGG: D00639
• RxNorm: 6926
• Wikipedia: Mexiletine
• TTD: D0X0RI
• LINCS BRD: BRD-A64092382

Synonyms

• dl-mexiletine
• (+/-)-Mexiletine
• (RS)-Mexiletine
• mexiletine hydrochloride
• mexiletin hydrochloride
• mexiletine HCl
• mexiletin HCl
• Mexiletina
• (rs)-mexiletine
• Dl-mexiletine
• Mexiletene
• Mexiletinum
• Mexilitine
• Mexityl
• Mexiletine HCL
• KO1173
• KO-1173
• KOE-1173
• Mexiletina [INN-Spanish]
• Mexiletine (INN)
• Mexiletine [INN:BAN]
• Mexiletinum [INN-Latin]
• Mexitil (TN)
• (+-)-1-(2,6-dimethylphenoxy)propan-2-amine
• (2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane
• 1-(2',6'-Dimethylphenoxy)-2-aminopropane
• 1-(2,6-Dimethylphenoxy)-2-propanamine
• 1-(2,6-dimethylphenoxy)propan-2-amine
• 1-Methyl-2-(2,6-xylyloxy)ethylamine
• 1-methyl-2-(2,6-xylyloxy)ethanamine
• 2-(2-Aminopropoxy)-1,3-DiMethyl-Benzene Hydrochloride
• 2-(2-aminopropoxy)-1,3-dimethylbenzene
• Mexitil
• 2-Propanamine, 1-(2,6-dimethylphenoxy)-
• ETHYLAMINE, 1-METHYL-2-(2,6-XYLYLOXY)-
• 1-(2,6-Dimethylphenoxy)-2-aminopropane
• CHEMBL558
• 1U511HHV4Z

Reported adverse events

• Eosinophilia
• Headache
• Nausea
• Vomiting
• Palpitations
• Tinnitus
• Constipation
• Rash
• Syncope
• Tremor
• Fatigue
• Arthralgia