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CAFFEINE
SynDRA canonical compound SYN0000861 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | RYR1 |
|---|
| Mechanism of action | Adenosine receptor antagonist |
|---|
| Indication | drowsiness | fatigue |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- ADORA2A
- ADORA1
- ADORA2B
- ADORA3
- ITPR1
- RYR1
- PIK3CD
- RYR3
- RYR2
- ATM
- PYGM
- PDE7B
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- Adenosine receptor antagonist
- ADORA1 ANTAGONIST
- ADORA2B ANTAGONIST
- ADORA3 ANTAGONIST
- ADORA2A ANTAGONIST
- ITPR1 ANTAGONIST
- RYR1 MODULATOR
- RYR2 MODULATOR
- RYR3 MODULATOR
Drug classes
- Central Nervous System Agents
- Central Nervous System Stimulants
- Enzyme Inhibitors
- Neurotransmitter Agents
- Phosphodiesterase Inhibitors
- Purinergic Antagonists
- Purinergic P1 Receptor Antagonists
- Central Nervous System Stimulant
- Methylxanthine
- Analgesics, Non-Narcotic
- Antimutagenic Agents
ATC classes
- N06B · PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DIAGNOSTIC AGENTS
Cross-references
Synonyms
- anhydrous caffeine
- peyona
- 1,3,7-trimethyl-2,6-dioxopurine
- 7-methyltheophylline
- cafalgine
- cafeina
- durvitan
- guaranine
- thein
- caffeine citrate
- caffeine, citrated
- nymusa
- Anhydrous caffeine
- Caffeine anhydrous
- Caffeinum
- Coffeinum
- Durvitan
- Guaranine
- Synalgos
- Vivarin
- FEMA NO. 2224
- NSC-5036
- Caffeine component of anoquan
- Caffeine component of cafergot
- Caffeine component of darvon compound
- Caffeine component of dhc plus
- Caffeine component of esgic
- Caffeine component of excedrin
- Caffeine component of femcet
- Caffeine component of fioricet
- Caffeine component of fiorinal
- Caffeine component of invagesic
- Caffeine component of invagesic forte
- Caffeine component of lanorinal
- Caffeine component of medigesic plus
- Caffeine component of migergot
- Caffeine component of norgesic
- Caffeine component of orphengesic
Reported adverse events
- Hepatotoxicity
- Acetaminophen
- TEN
- Addiction
- Caffeine
- Depression
- Accident
- Death
- ECT
- P
- Hypersensitivity
- Androgen deficiency
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