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SAQUINAVIR
SynDRA canonical compound SYN0000956 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CYP3A4 | CYP3A5 |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP3A4
- ABCB1
- Htr1a
- pol
- gag-pol
- TBXAS1
- TACR2
- SLC6A3
- OPRM1
- OPRK1
- OPRD1
- HTR1A
Mechanisms of action (all sources)
- protease inhibitor
- Inhibitor
- pol INHIBITOR
Drug classes
- HIV Protease Inhibitors
- Protease Inhibitor
- Cytochrome P450 3A Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Metabolic Side Effects of Drugs and Substances
- Protease Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- invirase
- saquinavir methanesulfonate
- sequinavir
- fortovase
- saquinavir mesylate
- saquinavir mesilate
- Saquinavirum
- RO-31-8959/000
- SCH-52852
- Fortovase
- Invirase
- ROC
- SQV
- Saguinavir
- Ro 318959
- Fortovase (TN)
- Fortovase(TM)
- Invirase (TN)
- Ro-31-8959
- Invirase(TM)(monomesylate)
- Saquinavir (JAN/USP/INN)
- QNC-ASN-HPH-DIQ-NTB
- CIS-N-TERT-BUTYL-DECAHYDRO-2-[2(R)-HYDROXY-4-PHENYL-3(S)-[[N-2-QUINOLYLCARBONYL-L-ASPARAGINYL]AMINO]BUTYL]-(4AS)-ISOQUINOLINE-3(S)-CARBOXAMIDE
- (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide
- (2s)-N-[(2s,3r)-4-[(2s,3s,4as,8as)-3-(Tert-Butylcarbamoyl)-3,4,4a,5,6,7,8,8a-Octahydro-1h-Isoquinolin-2-Yl]-3-Hydroxy-1-Phenyl-Butan-2-Yl]-2-(Quinolin-2-Ylcarbonylamino)butanediamide
- Ro-31-8959/000
- L3JE09KZ2F
- Sch 52852
- saquinavir (usp impurity)
- CHEBI:63621
- NSC722663
- Saquinivir
- saquinaviri mesilas
- RefChem:57420
- Monomethanesulfonate, Saquinavir
- DTXCID4024012
- J05AE01
- Ro 31 8959
Reported adverse events
- Diabetes mellitus
- Vomiting
- Bronchitis
- Constipation
- Eczema
- Fatigue
- Infection
- Influenza
- Nausea
- Pneumonia
- Pruritus
- Rash
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