← SynDRA
TRIAMTERENE
SynDRA canonical compound SYN0000963 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCNN1G |
|---|
| Mechanism of action | Sodium channel blocker |
|---|
| Indication | edema | hypertension | hypokalemia |
|---|
| Disease area | cardiology | endocrinology |
|---|
All known targets
- SCNN1A
- SCNN1B
- SCNN1G
- CASP1
- CTSG
- CYP2D6
- PTR1
- SCNN1A; SCNN1B; SCNN1G; SCNN1D
- SCNN1A|SCNN1B|SCNN1G
- SCNN1D
- SLC12A1
Mechanisms of action (all sources)
- Sodium channel blocker
- SCNN1A BLOCKER
- Amiloride-sensitive sodium channel, ENaC blocker
- SCNN1B BLOCKER
- SCNN1G BLOCKER
- SCNN1A|SCNN1B|SCNN1G MODULATOR
- Blocker
Drug classes
- Potassium-sparing Diuretic
- Diuretics
- Epithelial Sodium Channel Blockers
- Membrane Transport Modulators
- Natriuretic Agents
- Sodium Channel Blockers
ATC classes
- C03D · ALDOSTERONE ANTAGONISTS AND OTHER POTASSIUM-SPARING AGENTS
Cross-references
Synonyms
- diurene
- pterofen
- pterophene
- triamteren
- triamteril
- triteren
- Triamtereno
- NSC-639359
- NSC-77625
- SK&F-8542
- SK-8542
- Dyrenium
- Dytac
- Triamterene component of dyazide
- Triamterene component of maxzide
- Ademin
- Ademine
- Amteren
- Anjal
- Dazid
- Diarol
- Dinazide
- Diren
- Ditak
- Diucelpin
- Diurene
- Diutensat
- Diuteren
- Dyberzide
- Dyren
- Dytenzide
- Esiteren
- Hidiurese
- Hydrene
- Hypertorr
- Isobar
- Jatropur
- Jenateren
Reported adverse events
- Hyperkalemia
- Hypersensitivity
- Leukopenia
- Thrombocytopenia
- Stevens-Johnson syndrome
- Erythema multiforme
- Arrhythmia
- Diabetes mellitus
- Jaundice
- Xanthopsia
Look up TRIAMTERENE in the interactive SynDRA portal →