CELECOXIB

SynDRA canonical compound SYN0000994 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	PTGS2
Mechanism of action	Cyclooxygenase inhibitor
Indication	ankylosing spondylitis \| osteoarthritis \| primary dysmenorrhea (PD) \| rheumatoid arthritis
Disease area	endocrinology \| rheumatology

All known targets

PTGS2
CA12
PTGS1
PDPK1
PTGES
MAPK14
MT-CO1
MT-CO2
NCE103
PDE4A
PDE5A
PGR

Mechanisms of action (all sources)

Cyclooxygenase inhibitor
PTGS2 INHIBITOR
CA12 INHIBITOR
PTGS1 INHIBITOR

Drug classes

Cyclooxygenase Inhibitors
Analgesics
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Anti-Inflammatory Agents, Non-Steroidal
Antirheumatic Agents
Cyclooxygenase 2 Inhibitors
Enzyme Inhibitors
Peripheral Nervous System Agents
Sensory System Agents
Nonsteroidal Anti-inflammatory Drug

ATC classes

M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
L01X · OTHER ANTINEOPLASTIC AGENTS
SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
OPIOIDS

Cross-references

PubChem CID: 2662
ChEMBL: CHEMBL118
DrugBank: DB00482
ChEBI: CHEBI:41423
KEGG: D00567
RxNorm: 140587
PDB: CEL
Wikipedia: Celecoxib
TTD: D03RTS
LINCS BRD: BRD-K02637541

Synonyms

Reported adverse events

Perforation
Bleeding
GI bleed
Ulceration
Elderly
Headache
Hypertension
Rash
Nausea
Dizziness
Insomnia
Sinusitis

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