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PIOGLITAZONE
SynDRA canonical compound SYN0001035 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PPARG |
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| Mechanism of action | PPAR receptor agonist |
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| Indication | diabetes mellitus |
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| Disease area | endocrinology |
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All known targets
- PPARG
- TRPM3
- ABCB11
- MAOB
- Pparg
- Ppara
- PPARA
- Maob
- MAOA
- Abcb11
- INS
- Cisd1
Mechanisms of action (all sources)
- Insulin sensitizer
- PPAR receptor agonist
- PPARG AGONIST
- Peroxisome proliferator-activated receptor gamma agonist
- PPARG FULL AGONIST
- TRPM3 MODULATOR
- insulin sensitizer, ppar receptor agonist
Drug classes
- Peroxisome Proliferator-activated Receptor Activity
- Peroxisome Proliferator-activated Receptor alpha Agonists
- Peroxisome Proliferator-activated Receptor gamma Agonists
- Hypoglycemic Agents
- Peroxisome Proliferator Receptor alpha Agonist
- Peroxisome Proliferator Receptor gamma Agonist
- Thiazolidinedione
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- glustin
- sepioglin
- pioglitazone hydrochloride
- pioglitazone HCl
- Pioglitazona
- Duetact
- Zactos
- AD-4833
- U-72107
- Actos
- Pioglitazonum
- Glustin
- Pioglitazonum [INN-Latin]
- Pioglitazona [INN-Spanish]
- Pioglitazone [INN:BAN]
- Pioglitazone [BAN:INN]
- 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
- AD 4833
- CHEBI:8228
- Pioglitazone (Actos)
- HSDB 7322
- Actos (TN)
- 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
- C19H20N2O3S
- 5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-2,4-THIAZOLIDINEDIONE
- U 72107A
- Actost
- Glustin (TN)
- HS-0047
- Pioglitazone (INN)
- U72,107A
- Zactos (TN)
- (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
- (+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
- (+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
- 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-(9CI)
- 5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
- 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
Reported adverse events
- Lactic acidosis
- Lactic acid
- NGS
- Fracture
- Headache
- Myalgia
- Weight
- Sinusitis
- Pharyngitis
- Death
- Flatulence
- Acute coronary syndrome
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