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ZAFIRLUKAST
SynDRA canonical compound SYN0001085 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | CYSLTR1 |
| Mechanism of action | Leukotriene receptor antagonist |
| Indication | asthma |
| Disease area | pulmonary |
All known targets
- CYSLTR1
- CYSLTR2
- EPHX2
- PPARG
- ADORA3
- PLA2G4A
- SLC47A2
- SLC47A1
- SLC22A2
- SLC10A1
- PTGES
- MAPK14
Mechanisms of action (all sources)
- Leukotriene receptor antagonist
- CYSLTR1 ANTAGONIST
- Cysteinyl leukotriene receptor 1 antagonist
- CYSLTR2 ANTAGONIST
- EPHX2 INHIBITOR
- PPARG AGONIST
Drug classes
- Leukotriene Receptor Antagonists
- Anti-Asthmatic Agents
- Hormone Antagonists
- Leukotriene Antagonists
- Respiratory System Agents
- Leukotriene Receptor Antagonist
- Cytochrome P450 2C9 Inhibitors
ATC classes
- R03D · OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Cross-references
Synonyms
- ICI 204219
- ICI 204,219
- vanticon
- ICI-204219
- Accolate
- Accoleit
- Aeronix
- Olmoran
- Respix
- Zafirst
- AstraZeneca brand of zafirlukast
- Menarini brand of zafirlukast
- Novartis brand of zafirlukast
- Zeneca brand of zafirkulast
- Accolate (TN)
- Accoleit (TN)
- Vanticon (TN)
- Zafirlukast [USAN:BAN:INN]
- Accolate, Accoleit, Vanticon, Zafirlukast
- Zafirlukast (JAN/USAN/INN)
- Cyclopentyl N-[3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methylindol-5-yl]carbamate
- Cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate
- Cyclopentyl 3-[2-methoxy-4-(2-methylphenylsulfonylcarbamoyl)benzyl]-1-methyl-1H-indol-5-ylcarbamate
- Cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate
- Cyclopentyl (1-methyl-3-{[2-(methyloxy)-4-({[(2-methylphenyl)sulfonyl]amino}carbonyl)phenyl]methyl}-1H-indol-5-yl)carbamate
- Carbamic acid, (3-((2-methoxy-4-((((2-methylphenyl)sulfonyl)amino)carbonyl)phenyl)methyl)-1-methyl-1H-indol-5-yl)-, cyclopentyl ester
- 4-(5-cyclopentyloxy-carbonylamino-1-methyl-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide
- 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide
- 4-(5-cyclopentyloxycarbonylamino-2-methylindol-3-yl-methyl)-3-methoxy-N-O-tolylsulfonylbenzamide
- ICI-204,219
- XZ629S5L50
- DTXCID303746
- CHEBI:10100
- zafirlukastum
- RefChem:57963
- R03DC01
- MFCD00864775
- NCGC00164547-01
Reported adverse events
- Asthenia
- Dizziness
- Dyspepsia
- Hepatotoxicity
- Hypersensitivity
- Infection
- Myalgia
- Nausea
- Vomiting
- Headache
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