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MILTEFOSINE
SynDRA canonical compound SYN0001197 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | PLA2G1B |
| Mechanism of action | membrane integrity inhibitor |
| Indication | leishmaniasis |
| Disease area | infectious disease |
All known targets
Mechanisms of action (all sources)
- AKT1 INHIBITOR
- membrane integrity inhibitor
- PLA2G1B INHIBITOR
Drug classes
- Anti-Infective Agents
- Antifungal Agents
- Antineoplastic Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Antileishmanial
ATC classes
- P01C · AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
Cross-references
Synonyms
- impavido
- hexadecylphosphocholine
- hexadecylphosphorylcholine
- miltefos
- Miltefosina
- D-18506
- NSC-605583
- NSC-758968
- Impavido
- Miltex
- HDPC
- HePC
- Hexadecylphosphocholine
- Hexadecylphosphorylcholine
- Miltefosinum
- Baxter Oncology brand of miltefosine
- Baxter brand of miltefosine
- Miltefosin C
- Prasfarma brand of miltefosine
- IN1227
- H-1850
- M-7200
- Miltefosina [INN-Spanish]
- Miltefosine (INN)
- Miltefosine[INN:BAN]
- Miltefosinum [INN-Latin]
- N-Hexadecylphosphorylcholine
- TF-002
- Choline hydroxide, hexadecyl hydrogen phosphate, inner salt
- Choline, hexadecyl hydrogen phosphate, inner salt
- Hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
- Choline phosphate, hexadecyl ester, hydroxide, inner salt
- Choline phosphate, hexadecyl ester, hydroxide, inner salt (6CI)
- Hexadecyl 2-(trimethyl-.lambda.~5~-azanyl)ethyl hydrogen phosphate
- Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
- Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, innner salt
- 1-Hexadecylphosphorylcholine
- 2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide, inner salt
Reported adverse events
- Asthenia
- Dizziness
- Headache
- Lymphangitis
- Malaise
- Nausea
- Pruritus
- Pyrexia
- Somnolence
- Stevens-Johnson syndrome
- Vomiting
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