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MEROPENEM
SynDRA canonical compound SYN0001232 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Mechanism of action | bacterial cell wall synthesis inhibitor |
| Indication | intra-abdominal infections | meningitis | skin infections |
| Disease area | infectious disease |
All known targets
- bla OXA-48
- blaNDM-1
- blaVIM-2
- dacA
- dacB
- dacC
- pbpA
- ponA
- ska
Mechanisms of action (all sources)
- bacterial cell wall synthesis inhibitor
- dacB INHIBITOR
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
ATC classes
- J01D · OTHER BETA-LACTAM ANTIBACTERIALS
Cross-references
Synonyms
- meropenem hydrate
- merrem
- meropenem trihydrate
- Meropenem hydrate
- Meropenem trihydrate
- Meronem
- Meropenem (as trihydrate)
- Meropenem anhydrous
- Meropenem, anhydrous
- Merrem i.v.
- ICI 194,660
- ICI-194660
- NSC-759621
- SM-7338
- Meropenem component of vabomere
- Merrem
- MEPM
- MERONEM
- Meropen
- Mepem (TN)
- Meronem (TN)
- Meropen (TN)
- Meropenem (INN)
- Merrem (TN)
- Neopenem (TN)
- Merrem I.V. (TN)
- (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
- (2S,3R,4R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid
- (4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- (5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((S)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
- NSC 759621
- meropenem (usp impurity)
- Meropenem Hydrate
- SM 7338
- meropenem trihydrate (ep monograph)
- meropenem (usp monograph)
Reported adverse events
- Nausea
- Phlebitis
- Hypersensitivity
- Pain
- Rash
- Seizure
- Thrombocytopenia
- Vomiting
- Glossitis
- Injection site reaction
- Stevens-Johnson syndrome
- Death
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