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TRAZODONE
SynDRA canonical compound SYN0001233 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | SLC6A4 |
| Mechanism of action | Adrenergic receptor antagonist |
| Indication | depression |
| Disease area | neurology/psychiatry |
All known targets
- SLC6A4
- HTR2C
- HTR2A
- HTR2B
- HTR1A
- HRH1
- ADRA1A
- ADRA2A
- HTR7
- SLC6A3
- SLC6A2
- SIGMAR1
Mechanisms of action (all sources)
- Serotonin reuptake inhibitor
- Serotonin receptor antagonist
- Adrenergic receptor antagonist
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- HTR2B ANTAGONIST
- SLC6A4 MODULATOR
- HTR1A MODULATOR
Drug classes
- Anti-Anxiety Agents
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Central Nervous System Agents
- Central Nervous System Depressants
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Selective Serotonin Reuptake Inhibitors
- Serotonin Agents
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- trazodon
- trazodone hydrochloride
- trazodone HCl
- Trazodona
- Trittico
- J10.767K
- Beneficat
- Desirel
- Sideril
- Tradozone
- Trazalon
- Trazodil
- Trazodon
- Trazodonum
- Trazolan
- Trazonil
- Trialodine
- Desyrel Dividose
- Trazodona [Spanish]
- Trazodone Hcl
- Trazodonum [Latin]
- Beneficat (TN)
- Deprax (TN)
- Desirel (TN)
- Desyrel (TN)
- Desyrel(trazodone hcl salt)
- Molipaxin (TN)
- Thombran (TN)
- Trazodona [INN-Spanish]
- Trazodone (Desyrel)
- Trazodone (INN)
- Trazodone [INN:BAN]
- Trazodonum [INN-Latin]
- Trazorel (TN)
- Trialodine (TN)
- Trittico (TN)
- 2-(3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Reported adverse events
- Nausea
- Constipation
- Fatigue
- Headache
- Hypertension
- Hypotension
- Malaise
- Syncope
- Vomiting
- Disorientation
- Nervousness
- Tremor
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