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NEFAZODONE
SynDRA canonical compound SYN0001237 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Norepinephrine reuptake inhibitor |
|---|
All known targets
- HTR2A
- SLC6A4
- SLC6A2
- HTR2C
- CYP3A4
- ADRA1A
- SLC6A3
- HTR1A
- ABCB11
- Slc6a3
- Slc6a2
- Htr2a
Mechanisms of action (all sources)
- Adrenergic inhibitor
- Serotonin reuptake inhibitor
- Serotonin receptor antagonist
- Norepinephrine reuptake inhibitor
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
Drug classes
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Serotonin 5-HT2 Receptor Antagonists
- Serotonin Agents
- Serotonin and Noradrenaline Reuptake Inhibitors
- Serotonin Antagonists
- Serotonin Reuptake Inhibitor
ATC classes
Cross-references
Synonyms
- serzone
- nefazodone hydrochloride
- nefazodone HCl
- Nefazodona
- Nefazodonum
- Nefazodona [Spanish]
- Nefazodone Hcl
- Nefazodonum [Latin]
- Nefadar (TN)
- Nefazodone (INN)
- Nefazodone [INN:BAN]
- Serzone (TN)
- 1-(3-(4-(3-Chlorpheyl-1-piperazinylpropyl)-3-ethyl-4,5-dihydro-4-(2-phenoxyethyl)-1,2,4-triazol-5-on
- 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one
- 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
- 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
- 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-[2-(phenyloxy)ethyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
- CHEBI:7494
- Nefazodonum (Latin)
- RefChem:57773
- DTXCID203357
- N06AX06
- Nefadar
- NEFAZODONE [INN]
- SMR000550487
- NCGC00165846-02
- UNII-59H4FCV1TF
- SR-01000759312
- A1EAZ
- NEFAZODONE [MI]
- NEFAZODONE [VANDF]
- NEFAZODONE [WHO-DD]
- SCHEMBL35089
- MLS001165769
- MLS001195657
- BIDD:GT0789
- GTPL7247
Reported adverse events
- Abnormal dreams
- Anaphylactic reaction
- Arthralgia
- Asthenia
- Ataxia
- Breast pain
- Chills
- Constipation
- Cough
- Dizziness
- Dry mouth
- Dyspepsia
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