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PENTOXIFYLLINE
SynDRA canonical compound SYN0001266 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PDE5A |
|---|
| Mechanism of action | Phosphodiesterase inhibitor |
|---|
| Indication | claudication |
|---|
| Disease area | cardiology |
|---|
All known targets
- PDE4B
- PDE5A
- ADORA2B
- PDE4A
- TNF
- ADORA2A
- PDE6A
- PDE9A
- PDE8B
- PDE8A
- PDE7B
- PDE7A
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- ADORA2B ANTAGONIST
- Adenosine A2 receptor antagonist
- ADORA2A ANTAGONIST
- PDE5A INHIBITOR
- 3',5'-cyclic phosphodiesterase inhibitor
- PDE4A INHIBITOR
- PDE3A INHIBITOR
- PDE6H INHIBITOR
- PDE6G INHIBITOR
- PDE2A INHIBITOR
- PDE7A INHIBITOR
Drug classes
- Antioxidants
- Cardiovascular Agents
- Enzyme Inhibitors
- Free Radical Scavengers
- Hematologic Agents
- Phosphodiesterase Inhibitors
- Platelet Aggregation Inhibitors
- Protective Agents
- Radiation-Protective Agents
- Vasodilator Agents
- Blood Viscosity Reducer
ATC classes
- C04A · PERIPHERAL VASODILATORS
Cross-references
Synonyms
- azupentat
- dimethyloxohexylxanthine
- oxpentifylline
- pentoxifyllin
- Oxpentifylline
- Pentoxifilina
- Oxypentifylline
- Pentoxiphyllin
- BL-191
- C04AD03
- NSC-637086
- NSC-758481
- Neotren mr
- Pentoxil
- Trental
- Trental 100
- Trental 400
- Agapurin
- Azupentat
- Dimethyloxohexylxanthine
- Durapental
- Hemovas
- Ikomio
- PENTOXYPHYLINE;PNX
- Pentoxifyllin
- Pentoxifyllinum
- Pentoxiphylline
- Pentoxiphyllium
- Pentoxyfylline
- Pentoxyphyllin
- Pentoxyphylline
- Ralofect
- Rentylin
- Torental
- Trental;Vasofirin
- Vazofirin
- Agapurin Retard
- BL191
Reported adverse events
- Agitation
- Arrhythmia
- Dizziness
- Dyspepsia
- Flushing
- Headache
- Insomnia
- Nausea
- Nervousness
- Tremor
- Vomiting
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