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AMIODARONE
SynDRA canonical compound SYN0001275 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | KCNH2 |
|---|
| Mechanism of action | Potassium channel blocker |
|---|
| Indication | ventricular arrhythmias |
|---|
| Disease area | cardiology |
|---|
All known targets
- KCNH2
- KCNA7
- CHRM5
- CHRM3
- CACNA1H
- SCN5A
- ADRB1
- KDM5A
- Htr1b
- PHF2
- MC3R
- MC4R
Mechanisms of action (all sources)
- Potassium channel blocker
- KCNH2 BLOCKER
- HERG blocker
- KCNA7 MODULATOR
- CHRM5 POSITIVE ALLOSTERIC MODULATOR
Drug classes
- Antiarrhythmic
- Anti-Arrhythmia Agents
- Cardiovascular Agents
- Cytochrome P-450 CYP1A2 Inhibitors
- Cytochrome P-450 CYP2C9 Inhibitors
- Cytochrome P-450 CYP2D6 Inhibitors
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Membrane Transport Modulators
- Metabolic Side Effects of Drugs and Substances
- Potassium Channel Blockers
ATC classes
- C01B · ANTIARRHYTHMICS, CLASS I AND III
Cross-references
Synonyms
- amidorone
- sedacoron
- amiodarone hydrochloride
- amiodarone HCl
- Amiodarona
- Amidorone
- Aminodarone
- Amiobeta
- Amiodarex
- Amiodarons
- Amiodaronum
- Amiohexal
- Amjodaronum
- Ancar
- Aratac;Arycor
- Braxan
- Corbionax
- Cordarex
- Cordarone
- Kordaron
- Labaz
- Ortacrone
- Pacerone
- Rytmarone
- Sedacoron
- Sedacorone
- Tachydaron
- ASTA Medica Brand of Amiodarone Hydrochloride
- Alphapharm Brand of Amiodarone Hydrochloride
- Amiodarone Base
- Armstrong Brand of Amiodarone Hydrochloride
- Berenguer Infale Brand of Amiodarone Hydrochloride
- Betapharm Brand of Amiodarone Hydrochloride
- Cordarone Intravenous
- G Gam Brand of Amiodarone Hydrochloride
- Hexal Brand of Amiodarone Hydrochloride
- Leurquin Brand of Amiodarone Hydrochloride
- Pharma Investi Brand of Amiodarone Hydrochloride
Reported adverse events
- Pulmonary toxicity
- Liver injury
- Bradycardia
- Hypothyroidism
- Nausea
- Constipation
- Flushing
- Malaise
- Solar dermatitis
- Stevens-Johnson syndrome
- Arrhythmia
- Abdominal pain
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