VENLAFAXINE

SynDRA canonical compound SYN0001282 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	SLC6A4
Mechanism of action	Norepinephrine reuptake inhibitor
Indication	depression \| generalized anxiety disorder (GAD) \| panic disorders \| social anxiety disorder
Disease area	neurology/psychiatry

All known targets

SLC6A2
SLC6A4
Adra1a
CYP2C19
HTR2A
HTR2C
HTR6
NET
SLC6A3
Slc6a2
Slc6a3
Slc6a4

Mechanisms of action (all sources)

Adrenergic inhibitor
Serotonin reuptake inhibitor
Norepinephrine reuptake inhibitor
SLC6A4 INHIBITOR
Serotonin transporter inhibitor
SLC6A2 INHIBITOR
Norepinephrine transporter inhibitor
serotonin–norepinephrine reuptake inhibitor (SNRI)

Drug classes

Norepinephrine Uptake Inhibitors
Serotonin Uptake Inhibitors
Antidepressive Agents
Antidepressive Agents, Second-Generation
Central Nervous System Agents
Membrane Transport Modulators
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Psychotropic Drugs
Serotonin and Noradrenaline Reuptake Inhibitors
Serotonin and Norepinephrine Reuptake Inhibitor

ATC classes

N06A · ANTIDEPRESSANTS

Cross-references

PubChem CID: 5656
ChEMBL: CHEMBL637
DrugBank: DB00285
ChEBI: CHEBI:9943
KEGG: D00821
RxNorm: 39786
Wikipedia: Venlafaxine
TTD: D0P1UX
LINCS BRD: BRD-A51714012

Synonyms

Reported adverse events

Agitation
Asthenia
Chills
Constipation
Dizziness
Headache
Hypertension
Hypertonia
Insomnia
Mydriasis
Nausea
Nervousness

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