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VORICONAZOLE
SynDRA canonical compound SYN0001284 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS1 |
|---|
| Mechanism of action | Cytochrome P450 inhibitor |
|---|
| Indication | aspergillosis | esophageal candidiasis | skin infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP2C19
- CYP2C9
- CYP3A4
- CYP3A5
- PTGS1
- CYP11A1
- CYP46A1
- CYP51
- CYP51A1
- Candi ERG11
- ERG11
- cyp51
Mechanisms of action (all sources)
- Cytochrome P450 inhibitor
- Modulator
- ERG11 INHIBITOR
Drug classes
- Azole Antifungal
- Cytochrome P450 2C19 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- Cytochrome P450 2C9 Inhibitors
- 14-alpha Demethylase Inhibitors
- Anti-Infective Agents
- Antifungal Agents
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Hormone Antagonists
- Metabolic Side Effects of Drugs and Substances
ATC classes
- J02A · ANTIMYCOTICS FOR SYSTEMIC USE
Cross-references
Synonyms
- voriconazol
- vfend
- UK109496
- UK 109496
- Voriconazol
- NSC-759888
- UK-109,496
- UK-109496
- Vfend
- Voriconazole accord
- Voriconazole hikma (previously voriconazole hospira)
- VCZ
- Pfizer brand of voriconazole
- Voriconazole in combination with MGCD290
- DRG-0301
- VFEND (TN)
- Vfend, Voriconazole
- Voriconazole [USAN:INN:BAN]
- Voriconazole (JAN/USAN/INN)
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
- (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
- (alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
- (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
- VRC
- voriconazole (usp-rs)
- voriconazole (usp monograph)
- JFU09I87TR
- voriconazole (ep monograph)
- NSC 759888
- Voriconazolum
- CHEBI:10023
- DTXCID3026485
- RefChem:56222
- UK109,496
- J02AC03
- (+/-)-Voriconazole
- Voriconazole Vfend
Reported adverse events
- Stevens-Johnson syndrome
- Rash
- Arrhythmia
- Chills
- Chromatopsia
- Fluorosis
- Hallucination
- Headache
- Nausea
- Photophobia
- Tachycardia
- Vomiting
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