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TRIMIPRAMINE
SynDRA canonical compound SYN0001292 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Norepinephrine reputake inhibitor |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A2
- SLC6A3
- SLC6A4
- HRH1
- ADRA1A
- ADRA1B
- ADRA1D
- CACNA1B
- DRD2
- HTR2A
- HTR2C
- SLC22A1
Mechanisms of action (all sources)
- Tricyclic antidepressant
- Norepinephrine reputake inhibitor
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Tricyclic Antidepressant
ATC classes
Cross-references
Synonyms
- rhotrimine
- trimeprimine
- trimeproprimine
- trimipramine maleate
- surmontil
- trimipramine maleate salt
- trimipramine mesylate
- trimipramine monohydrochloride
- Trimipramina
- Trimeproprimine
- 7162-RP
- IL-6001
- Sapilent
- Stangyl
- Surmontil
- Surmontyl
- Trimeprimina
- Trimeprimine
- Trimeproprimin
- Trimipraminum
- Trimeprimina [Italian]
- FI 6120
- Beta-Methylimipramine
- RP-7162
- Rhotrimine (TN)
- Stangyl (TN)
- Surmontil (TN)
- Trimipramina [INN-Spanish]
- Trimipraminum [INN-Latin]
- Trimipramine (USAN/INN)
- Trimipramine [USAN:INN:BAN]
- Trimipramine, (-)-Isomer
- (+)-Trimipramine
- (-)-Trimipramine
- 1-(3-Dimethylamino-2-methylpropyl)-4,5-dihydro-2,3:6,7-dibenzazepine
- 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine
- 10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz(b,f)azepine
- 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine
Reported adverse events
- Confusional state
- Dry mouth
- Hypotension
- Jaundice
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