METHYLPREDNISOLONE

SynDRA canonical compound SYN0001303 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	NR3C1
Mechanism of action	Glucocorticoid receptor agonist
Indication	allergic rhinitis \| anemia \| ankylosing spondylitis \| bursitis \| enteritis \| hypercalcemia \| multiple sclerosis \| mycosis \| osteoarthritis \| psoriasis \| psoriatic arthritis \| seborrheic dermatitis \| thyroiditis \| ulcerative colitis
Disease area	allergy \| dermatology \| endocrinology \| gastroenterology \| hematology \| infectious disease \| neurology/psychiatry \| rheumatology

All known targets

NR3C1
ANXA1
AR
TRPC5

Mechanisms of action (all sources)

NR3C1 AGONIST
NR3C1 MODULATOR

Drug classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid
Anti-Inflammatory Agents
Antiemetics
Central Nervous System Agents
Gastrointestinal Agents
Glucocorticoids
Hormones
Neuroprotective Agents
Peripheral Nervous System Agents
Protective Agents

ATC classes

H02B · CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS
D07A · CORTICOSTEROIDS, PLAIN
D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION

Cross-references

PubChem CID: 6741
ChEMBL: CHEMBL650
DrugBank: DB00959
ChEBI: CHEBI:6888
KEGG: D00407
RxNorm: 6902
Wikipedia: Methylprednisolone
TTD: D08PIQ
LINCS BRD: BRD-K35240538

Synonyms

Reported adverse events

Cardiac arrest
Exophthalmos
Fluid retention
Cushingoid
Headache
Sodium retention
Urticaria
Vertigo
Osteoporosis
Hypertension
Glaucoma
Tendon rupture

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