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DIPHENHYDRAMINE
SynDRA canonical compound SYN0001312 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HRH1
- CHRM1
- HTR2C
- SLC6A3
- SLC6A2
- SLC22A2
- SCN3A
- SCN2A
- SCN1A
- KCNH2
- HTR2B
- CHRM2
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- HNMT INHIBITOR
Drug classes
- Histamine H1 Receptor Antagonists
- Histamine-1 Receptor Antagonist
- Anesthetics
- Anesthetics, Local
- Anti-Allergic Agents
- Antiemetics
- Central Nervous System Agents
- Central Nervous System Depressants
- Gastrointestinal Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
ATC classes
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- benadryl
- diphenhydramine salicylate
- diphenhydramine laurylsulfate
- benzhydramine
- probedryl
- diphenhydramine hydrochloride
- diphenhydramine citrate
- diphenhydramine HCl
- Difenhidramina
- Diphenhdyra
- Restamin
- Benadryl
- Benzhydramine
- Probedryl
- Alledryl
- Antistominum
- Dihidral
- 2-(Benzhydryloxy)-N,N-dimethylethanamine
- Benzhydraminum
- Benzhydroamina
- Diphantine
- Difenhydramin
- Ibiodral
- Difedryl
- Dibondrin
- Mephadryl
- Desentol
- Dermistina
- Betramin
- Benzhydril
- Benzantine
- Benachlor
- Bagodryl
- Syntedril
- Novamina
- Medidryl
- Hyadrine
- Histaxin
Reported adverse events
- Hypotension
- Sedation
- Urticaria
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