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PROTRIPTYLINE
SynDRA canonical compound SYN0001331 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Tricyclic antidepressant |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A2
- SLC6A4
- ADORA3
- CACNA1B
- CHRM1
- CHRM2
- CHRM3
- CHRM4
- CHRM5
- HRH1
- HTR2A
- HTR2B
Mechanisms of action (all sources)
- Tricyclic antidepressant
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Tricyclic Antidepressant
ATC classes
Cross-references
Synonyms
- protryptyline
- triptil
- protriptyline hydrochloride
- protriptyline HCl
- Protriptilina
- Amimetilina
- Impril
- Maximed
- Novopramine
- Protriptylinum
- Protryptyline
- Rhotrimine
- Triptil
- Triptyl
- Vivactil
- Vivactyl
- Triptil hydrochloride
- Normethyl EX4442
- Triadapin 5
- Apo-Imipramine
- Apo-Trimip
- Novo-Doxepin
- Novo-Tripramine
- Protriptilina [INN-Spanish]
- Protriptyline (INN)
- Protriptyline [INN:BAN]
- Protriptylinum [INN-Latin]
- Vivactil (TN)
- N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine
- N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine
- N-Methyl-5H-dibenzo(a,d)cycloheptene-5-propylamine
- N-3-(5H-Dibenzo(a,d)cyclohepten-5-yl)propyl-N-methylamine
- 3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine
- 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
- 5-(3-Methylaminopropyl)-5H-Dibenzo[a,d]cycloheptene
- 5-(3-Methylaminopropyl)-5H-dibenzo(a,d)cycloheptene
- 5H-Dibenzo[a, d]cycloheptene-5-propanamine, N-methyl-, hydrochloride
- 7-(3-Methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene
Reported adverse events
- Agranulocytosis
- Confusional state
- Jaundice
- Myocardial infarction
- Nausea
- Seizure
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