EPINEPHRINE

SynDRA canonical compound SYN0001364 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ADRB3
Mechanism of action	Adrenergic receptor agonist
Indication	anaphylactic shock \| asthma \| cardiac arrest
Disease area	allergy \| cardiology \| pulmonary

All known targets

ADRB1
ADRA1A
ADRA1D
ADRA2A
ADRA2B
ADRA2C
ADRB2
ADRA1B
ADRB3
Adrb2
SLC6A2
PAH

Mechanisms of action (all sources)

Neurotransmitter
Adrenergic receptor agonist
ADRA1A AGONIST
ADRA2A AGONIST
ADRB1 AGONIST
ADRB2 AGONIST
ADRA2C AGONIST
ADRA1D AGONIST
ADRA1B AGONIST
ADRA2B AGONIST
ADRB3 AGONIST
carbonic anhydrase activator

Drug classes

Adrenergic alpha-Agonists
Adrenergic beta-Agonists
alpha-Adrenergic Agonist
beta-Adrenergic Agonist
Catecholamine
Adrenergic Agents
Adrenergic Agonists
Anti-Asthmatic Agents
Bronchodilator Agents
Cardiovascular Agents
Mydriatics
Neurotransmitter Agents

ATC classes

R03A · ADRENERGICS, INHALANTS
S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
B02B · VITAMIN K AND OTHER HEMOSTATICS
A01A · STOMATOLOGICAL PREPARATIONS
C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES

Cross-references

PubChem CID: 5816
ChEMBL: CHEMBL679
DrugBank: DB00668
ChEBI: CHEBI:28918
KEGG: D00996
RxNorm: 3992
PDB: ALE
Wikipedia: Epinephrine (medication)
TTD: D04PHC
LINCS BRD: BRD-K63126190

Synonyms

Reported adverse events

Cardiac arrest
Arrhythmia
Clostridial infection
Hypertension
Nausea
Bradycardia
Headache
Adverse reaction
Hypotension
Chondrolysis
Infusion
Epinephrine

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