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BACLOFEN
SynDRA canonical compound SYN0001489 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABBR2 |
|---|
| Mechanism of action | GABA receptor agonist |
|---|
| Indication | multiple sclerosis | spasms |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GABBR2
- GABBR1
- ADORA3
- Gabrb2
- KCTD16
- KCTD12
- Gabrq
- Gabrp
- Gabrg3
- Gabrg2
- Gabrg1
- Gabre
Mechanisms of action (all sources)
- GABA receptor agonist
- GABBR1 AGONIST
- GABA-B receptor agonist
- GABBR2 AGONIST
- GABBR1|GABBR2|KCTD8|KCTD12|KCTD16 FULL AGONIST
- benzodiazepine receptor agonist
- Modulator
Drug classes
- GABA B Agonists
- GABA A Agonists
- Central Nervous System Agents
- GABA Agents
- GABA Agonists
- GABA-B Receptor Agonists
- Muscle Relaxants, Central
- Neuromuscular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- gamma-Aminobutyric Acid-ergic Agonist
ATC classes
- M03B · MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
Cross-references
Synonyms
- baclon
- lioresal
- DL-Baclofen
- Baclofene
- Baclofeno
- (rs)-baclofen
- Fleqsuvy
- Lyvispah
- BA-34,647
- BA-34647
- NSC-755906
- Baclospas-10
- Gablofen
- Kemstro
- Lioresal
- Lioresal intrath
- Lyflex
- Ozobax
- Ozobax ds
- Arbaclofen
- (R)-Baclofen
- (R)-4-Amino-3-(4-chlorophenyl)butanoic acid
- d-Baclofen
- (-)-Baclofen
- (R)-(-)-Baclofen
- R-Baclofen
- R-(-)-Baclofen
- STX209
- (3R)-4-amino-3-(4-chlorophenyl)butanoic acid
- UNII-NYU6UTW25B
- l-Baclofen
- STX 209
- (R)-4-Amino-3-(4-chlorophenyl)butyric Acid
- NYU6UTW25B
- CHEMBL301742
- AK109161
- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, (R)-
- Benzeneporopanoic acid, (beta-(aminomethyl)-4-chloro-, (betaR)-
Reported adverse events
- Nausea
- Hypotension
- Sedation
- Constipation
- Headache
- Insomnia
- Dizziness
- Epilepsy
- Fatigue
- Schizophrenia
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