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MESALAMINE
SynDRA canonical compound SYN0001504 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Prostanoid receptor antagonist |
|---|
| Indication | inflammatory bowel disease | ulcerative colitis |
|---|
| Disease area | gastroenterology |
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All known targets
- PPARG
- PTGS1
- ALOX5
- PTGS2
- CHUK
- CTNNB1
- Hao1
- IKBKB
- MPO
- NAT1
- TNF
Mechanisms of action (all sources)
- Lipoxygenase inhibitor
- Cyclooxygenase inhibitor
- Prostanoid receptor antagonist
- ALOX5 INHIBITOR
- Arachidonate 5-lipoxygenase inhibitor
- PPARG AGONIST
- Peroxisome proliferator-activated receptor gamma agonist
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- PPARG FULL AGONIST
Drug classes
- Aminosalicylate
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
Cross-references
Synonyms
- mesalazine
- 5-ASA
- 2-Hydroxy-5-aminobenzoic acid
- 3-Carboxy-4-hydroxyaniline
- 5-Amino-2-hydroxybenzoic acid
- 5-Aminosalicylic acid
- claversal
- mesacol
- mesalsal
- mesasal
- m-Aminosalicylic acid
- mesalamine hydrochloride
- mesalamine HCl
- Mesalazine
- Mesalazina
- Benzoic acid, 5-amino-2-hydroxy-
- Fisalamine
- Iialda
- MAX-002
- NSC-38877
- Apriso
- Asacol
- Asacol hd
- Canasa
- Coltec ec
- Delzicol
- Ipocol
- Lialda
- Mesren mr
- Mezavant xl
- Octasa
- Pentasa
- Pentasa sr
- Rowasa
- Salofalk
- Sfrowasa
- Asacolitin
- Asacolon
Reported adverse events
- Hypersensitivity
- Rash
- Renal impairment
- Stevens-Johnson syndrome
- Nephrolithiasis
- Flatulence
- Severe cutaneous adverse reaction
- Headache
- Dizziness
- Abdominal pain
- Alopecia
- Dyspepsia
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